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PubMed ID: 9849822 Johansen PB et al

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19, 1354 (2024), Abstract Impairment of lipid homeostasis causes lysosomal accumulation of endogenous protein aggregates through ESCRT disruption.: Yong, J., Villalta, J

PHL also has nephroprotective effects and is helpful in the treatment of hyperuricemia-related renal disorders since it simultaneously inhibits nucleotide-binding domain, leucine-richcontaining family, pyrin domaincontaining-3 (NLRP3) and uric acid reabsorption and attenuates uric acid-induced renal impairment 50